Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | LDHB | P07195 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231511 | 0.92 | ALOX5 (0.41) | TSHRHTTLMNACYP3A4GAA | |
| SCHEMBL6232980 | 0.87 | CYSLTR2 (0.40) | LMNAMEN1KMT2A | |
| SCHEMBL6233436 | 0.86 | CYSLTR2 (0.42) | TSHRLMNAMEN1KMT2AHSD17B10 | |
| SCHEMBL5590632 | 0.83 | TSHR (0.47) | TSHRHTTLMNACYP3A4GAA | |
| SCHEMBL5587238 | 0.82 | HMGCR (0.36) | TSHRLDHALDHBTHRB | |
| SCHEMBL6233287 | 0.81 | ALOX5 (0.50) | CYP3A4MEN1KMT2AHSD17B10LDHA | |
| SCHEMBL6233270 | 0.81 | CYP1A2 (0.44) | TSHRLMNAMEN1KMT2AHSD17B10 | |
| SCHEMBL6233139 | 0.81 | ALOX5 (0.41) | LMNATHRBALOX5 | |
| SCHEMBL6233682 | 0.80 | ALOX5 (0.40) | MEN1KMT2ATHRBALOX5 | |
| SCHEMBL6234043 | 0.79 | ALOX5 (0.49) | TSHRHTTLMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |