Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HMGCR | P04035 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231507 | 0.90 | ALOX5 (0.57) | ALOX5TSHRTUBB1ESR1HTR2A | |
| SCHEMBL6232977 | 0.85 | ALOX5 (0.48) | ALOX5HMGCR | |
| SCHEMBL6233429 | 0.83 | ALOX5 (0.54) | ALOX5HMGCRESR1LMNA | |
| SCHEMBL5590629 | 0.80 | TSHR (0.47) | TSHRTUBB1ESR1HTR2AHTR2C | |
| SCHEMBL6234046 | 0.79 | TSHR (0.42) | ALOX5TSHRHTTLMNAALDH1A1 | |
| SCHEMBL6233280 | 0.77 | ALOX5 (0.77) | ALOX5TSHRHMGCRTUBB1HTR2A | |
| SCHEMBL6233136 | 0.77 | ALOX5 (0.57) | ALOX5ESR1HTTLMNAALDH1A1 | |
| SCHEMBL6233674 | 0.76 | ALOX5 (0.56) | ALOX5ESR1HTT | |
| SCHEMBL6233266 | 0.75 | ESR1 (0.43) | ESR1LMNAALDH1A1GABRA1GABRB2 | |
| SCHEMBL28625199 | 0.74 | TSHR (0.48) | TSHRTUBB1ESR1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |