Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | KCNH3 | Q9ULD8 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13363711 | 0.84 | TDP1 (0.70) | CTSKTDP1KCNH3 | |
| SCHEMBL6235242 | 0.83 | CTSK (0.76) | CTSKTDP1 | |
| SCHEMBL6237210 | 0.82 | TDP1 (0.75) | CTSKTDP1KCNH3 | |
| SCHEMBL6236332 | 0.78 | TDP1 (0.66) | CTSKTDP1KCNH3 | |
| SCHEMBL3408870 | 0.78 | TDP1 (0.65) | CTSKTDP1KCNH3 | |
| SCHEMBL6240085 | 0.76 | TDP1 (0.70) | CTSKTDP1KCNH3 | |
| SCHEMBL6237020 | 0.76 | TDP1 (0.58) | CTSKTDP1KCNH3 | |
| SCHEMBL6240598 | 0.75 | TDP1 (0.68) | CTSKTDP1KCNH3 | |
| SCHEMBL6239975 | 0.74 | TDP1 (0.56) | CTSKTDP1 | |
| SCHEMBL796672 | 0.73 | CTSK (0.61) | CTSKTDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011703-A1 | 2-CYANO-1,3,5-TRIAZINE-4,6-DIAMINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |