Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.55 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3289406 | 0.90 | KCNH3 (0.69) | KCNH3SLC2A1MAPTNPSR1L3MBTL1 | |
| SCHEMBL13325954 | 0.80 | APP (0.67) | KCNH3SLC2A1MAPTNPSR1L3MBTL1 | |
| SCHEMBL13363711 | 0.79 | TDP1 (0.70) | TDP1KCNH3ADORA2ACTSK | |
| SCHEMBL6235242 | 0.78 | CTSK (0.76) | TDP1ADORA2ACTSKMAPT | |
| SCHEMBL3287006 | 0.77 | CTSL (0.61) | KCNH3SLC2A1CTSKCTSLCTSS | |
| SCHEMBL10073747 | 0.77 | KCNH3 (0.77) | TDP1KCNH3ADORA2AADORA2BSLC2A1 | |
| SCHEMBL10099686 | 0.77 | KCNH3 (0.77) | TDP1KCNH3ADORA2AADORA2BSLC2A1 | |
| SCHEMBL6237210 | 0.77 | TDP1 (0.75) | TDP1KCNH3CTSK | |
| SCHEMBL6237023 | 0.76 | ADORA2A (0.53) | ADORA2AADORA2BCTSKCTSLCTSS | |
| SCHEMBL6234331 | 0.76 | CTSK (0.68) | TDP1KCNH3CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011703-A1 | 2-CYANO-1,3,5-TRIAZINE-4,6-DIAMINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |