Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | CASP1 | P29466 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | CASP7 | P55210 | 1/20 | 0.68 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 9/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6716483 | 0.83 | KMT2A (0.52) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL16274465 | 0.82 | KMT2A (0.60) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL6232018 | 0.79 | KDM4E (0.55) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL5779207 | 0.77 | ALDH1A1 (0.52) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL10092656 | 0.77 | MEN1 (0.57) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL31590791 | 0.76 | ALDH1A1 (0.67) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL30945840 | 0.74 | ALDH1A1 (0.97) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL6197333 | 0.74 | ALDH1A1 (0.97) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL16274458 | 0.73 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL1076966 | 0.72 | ALDH1A1 (0.59) | KMT2AMEN1ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089903-A9 | PIPERIDINE DERIVATIVES AS RENIN INHIBITORS FOR THE TREATMENT OF HYPERTENSION | WARNER LAMBERT CO (US) | 2005-10-27 | — | — | WO | disclosed |