Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.67 |
| ▸ | GAA | P10253 | 12/20 | 0.67 |
| ▸ | MAPT | P10636 | 8/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | CASP1 | P29466 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | CASP7 | P55210 | 1/20 | 0.67 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10784314 | 0.87 | ALDH1A1 (0.52) | ALDH1A1GAAMAPTKDM4EKMT2A | |
| SCHEMBL8728819 | 0.84 | ALDH1A1 (0.53) | ALDH1A1GAAMAPTKDM4EKMT2A | |
| SCHEMBL31020834 | 0.81 | ALDH1A1 (0.59) | ALDH1A1GAAMAPTKDM4EKMT2A | |
| SCHEMBL1076966 | 0.81 | ALDH1A1 (0.59) | ALDH1A1GAAMAPTKDM4EKMT2A | |
| SCHEMBL31020835 | 0.81 | ALDH1A1 (0.59) | ALDH1A1GAAMAPTKDM4EKMT2A | |
| SCHEMBL10493943 | 0.81 | ATAD2 (0.53) | ALDH1A1GAAMAPTKDM4EKMT2A | |
| SCHEMBL12956755 | 0.79 | ALDH1A1 (0.59) | ALDH1A1GAAMAPTKDM4EKMT2A | |
| SCHEMBL23128840 | 0.78 | HSD17B3 (0.52) | ALDH1A1GAAMAPTKDM4EKMT2A | |
| SCHEMBL8728886 | 0.78 | HDAC1 (0.52) | ALDH1A1GAAMAPTKDM4EKMT2A | |
| SCHEMBL12656517 | 0.78 | HDAC1 (0.53) | ALDH1A1GAAMAPTKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260097029-A1 | Tetrahydroquinoline Compounds As Antitumor Agents | COSCONATI SANDRO (IT) | 2026-04-09 | — | — | US | disclosed |
| CN-120051458-A | Tetrahydroquinoline compounds as antitumor agents | 桑德罗·科斯科纳蒂 | 2025-05-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260097029-A1 | Tetrahydroquinoline Compounds As Antitumor Agents | BCOR, MCL1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | ALDH1A1 1372/4885GAA 4067/4885MAPT 4765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.