Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.31 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
| ▸ | CTSA | P10619 | 1/20 | 0.30 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6271288 | 0.82 | PTPRZ1 (0.38) | PTPRZ1PPARDNTRK1CSF1RNTRK2 | |
| SCHEMBL6234948 | 0.82 | PTPRZ1 (0.38) | PTPRZ1PPARDNTRK1CSF1RNTRK2 | |
| SCHEMBL6231278 | 0.82 | PTPRZ1 (0.41) | PTPRZ1PPARDNTRK1CSF1RNTRK2 | |
| SCHEMBL6231277 | 0.78 | PTPRZ1 (0.41) | PTPRZ1PPARDNTRK1CSF1RNTRK2 | |
| SCHEMBL6271280 | 0.76 | PTPRZ1 (0.39) | PTPRZ1PPARDCTSA | |
| SCHEMBL6234945 | 0.76 | PTPRZ1 (0.39) | PTPRZ1PPARDCTSA | |
| SCHEMBL6232926 | 0.75 | PTPRZ1 (0.42) | PTPRZ1PPARDHTR2AALDH1A1 | |
| SCHEMBL6236911 | 0.72 | PLK1 (0.48) | NTRK1CSF1RNTRK2ALDH1A1LMNA | |
| SCHEMBL6232104 | 0.71 | PTPRZ1 (0.42) | PTPRZ1PPARDNTRK1CSF1RNTRK2 | |
| SCHEMBL6256021 | 0.71 | PTPRZ1 (0.42) | PTPRZ1PPARDNTRK1CSF1RNTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |