SCHEMBL6234898

SCHEMBL6234898

Cc1[nH]nc(N)c1-c1nc2cc(F)ccc2s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ILK Q13418 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL686711 0.90 ILK (1.00) ILK
SCHEMBL686521 0.84 ILK (1.00) ILK
SCHEMBL686453 0.83 ILK (0.70) ILK
SCHEMBL686598 0.81 ILK (1.00) ILK
SCHEMBL2165749 0.80 ILK (0.66) ILK
SCHEMBL687512 0.80 ILK (1.00) ILK
SCHEMBL686578 0.78 ILK (1.00) ILK
SCHEMBL687596 0.77 ILK (0.63) ILK
SCHEMBL686474 0.77 ILK (1.00) ILK
SCHEMBL687024 0.76 ILK (1.00) ILK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1542997-A2 PYRAZOLYLBENZOTHIAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS QLT, Inc. (CA) 2005-06-22 EP disclosed
WO-2004011460-A2 PYRAZOLYLBENZOTHIAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS QLT, INC. (CA) 2004-02-05 WO disclosed