Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.50 |
| ▸ | MPI | P34949 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6258346 | 0.80 | ALDH1A1 (0.52) | ALDH1A1RAB9AMAPK1MEN1KMT2A | |
| SCHEMBL6582029 | 0.78 | MEN1 (0.55) | ALDH1A1MEN1KMT2A | |
| SCHEMBL28561369 | 0.78 | ALDH1A1 (0.50) | ALDH1A1RAB9AMAPK1MEN1KMT2A | |
| SCHEMBL6582022 | 0.78 | MEN1 (0.55) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6229878 | 0.77 | ALDH1A1 (0.71) | ALDH1A1RAB9AMAPK1MEN1KMT2A | |
| SCHEMBL8027350 | 0.77 | ALDH1A1 (0.60) | ALDH1A1RAB9AMAPK1MEN1KMT2A | |
| SCHEMBL29116234 | 0.77 | ALDH1A1 (0.52) | ALDH1A1RAB9AMAPK1MEN1KMT2A | |
| SCHEMBL15712185 | 0.77 | ALDH1A1 (0.61) | ALDH1A1RAB9AMAPK1MEN1KMT2A | |
| SCHEMBL4978822 | 0.77 | ALDH1A1 (0.55) | ALDH1A1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL14315230 | 0.75 | ALDH1A1 (0.51) | ALDH1A1RAB9AMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092181-A9 | HETEROCYCLIC MCHR1 ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2005-01-27 | — | — | WO | disclosed |