Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582029 | 1.00 | MEN1 (0.55) | MEN1KMT2AALDH1A1NFE2L2 | |
| SCHEMBL6832723 | 0.85 | MEN1 (0.46) | MEN1KMT2AALDH1A1NFE2L2 | |
| SCHEMBL6832721 | 0.85 | MEN1 (0.46) | MEN1KMT2AALDH1A1NFE2L2 | |
| SCHEMBL6099735 | 0.80 | MEN1 (0.77) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6099740 | 0.80 | MEN1 (0.77) | MEN1KMT2AALDH1A1 | |
| SCHEMBL8551282 | 0.78 | PDE10A (0.54) | MEN1KMT2AALDH1A1 | |
| SCHEMBL8551275 | 0.78 | PDE10A (0.54) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6234925 | 0.78 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6582603 | 0.78 | MAPT (0.50) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6585280 | 0.78 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846689-B1 | Benzimidazole compounds | PFIZER (US) | 2004-01-14 | — | — | EP | claimed |
| EP-0846689-A1 | Benzimidazole compounds | PFIZER INC. (US) | 1998-06-10 | — | — | EP | claimed |
| JP-10168066-A | — | — | None | — | — | JP | disclosed |
| EP-0846689-B1 | Benzimidazole compounds | PFIZER (US) | 2004-01-14 | — | — | EP | disclosed |
| JP-H10168066-A | BENZIMIDAZOLE COMPOUND | PFIZER PHARMACEUT INC | 1998-06-23 | — | — | JP | disclosed |
| EP-0846689-A1 | Benzimidazole compounds | PFIZER INC. (US) | 1998-06-10 | — | — | EP | disclosed |