Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235063 | 1.00 | CTSL (0.46) | CTSLCTSBCTSSALDH1A1DDB1 | |
| SCHEMBL6231440 | 0.99 | ALDH1A1 (0.46) | CTSLCTSBCTSSALDH1A1DDB1 | |
| SCHEMBL4867759 | 0.88 | ALDH1A1 (0.44) | ALDH1A1DDB1CRBN | |
| SCHEMBL4868005 | 0.87 | ALDH1A1 (0.45) | CTSLCTSBCTSSALDH1A1DDB1 | |
| SCHEMBL4864688 | 0.87 | ALDH1A1 (0.45) | CTSLCTSBCTSSALDH1A1DDB1 | |
| SCHEMBL4863360 | 0.85 | ALDH1A1 (0.46) | CTSLCTSBCTSSALDH1A1DDB1 | |
| SCHEMBL6236356 | 0.85 | GAA (0.43) | ALDH1A1DDB1CRBNFKBP1A | |
| SCHEMBL4864647 | 0.85 | GAA (0.43) | ALDH1A1DDB1CRBNFKBP1A | |
| SCHEMBL4869754 | 0.84 | CYP3A4 (0.42) | ALDH1A1 | |
| SCHEMBL6236539 | 0.83 | ALDH1A1 (0.40) | ALDH1A1DDB1CRBNFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005456-A2 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-01-20 | — | — | WO | disclosed |