Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.61 |
| ▸ | CTSL | P07711 | 9/20 | 0.61 |
| ▸ | CTSS | P25774 | 9/20 | 0.61 |
| ▸ | CTSB | P07858 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | IDH2 | P48735 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239838 | 0.86 | NPSR1 (0.74) | CTSKCTSLCTSSCTSBLMNA | |
| SCHEMBL14504271 | 0.80 | LMNA (0.66) | LMNASMN1; SMN2HTTNPSR1IDH2 | |
| SCHEMBL5257444 | 0.79 | CTSK (0.62) | CTSKCTSLCTSSCTSBLMNA | |
| SCHEMBL6238387 | 0.78 | LMNA (0.62) | CTSKCTSLCTSSCTSBLMNA | |
| SCHEMBL6236443 | 0.78 | NPSR1 (0.60) | CTSKCTSLCTSSCTSBLMNA | |
| SCHEMBL5257330 | 0.78 | CTSK (0.64) | CTSKCTSLCTSSCTSBLMNA | |
| SCHEMBL5254103 | 0.75 | CTSK (0.64) | CTSKCTSLCTSSCTSBLMNA | |
| SCHEMBL6238170 | 0.75 | GBA1 (0.60) | CTSKCTSLCTSSCTSBLMNA | |
| SCHEMBL6239346 | 0.75 | GBA1 (0.60) | CTSKCTSLCTSSCTSBLMNA | |
| SCHEMBL6275061 | 0.74 | NPSR1 (0.55) | CTSKCTSLCTSSCTSBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011703-A1 | 2-CYANO-1,3,5-TRIAZINE-4,6-DIAMINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |