SCHEMBL6234993

SCHEMBL6234993

CC(C)C(C(=O)O)C(O)CC#N

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.35
DPP4 P27487 1/20 0.32
OR51E2 Q9H255 1/20 0.31
SLC7A5 Q01650 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6234803 0.82 CTSS (0.34) TP53DPP4
SCHEMBL16667373 0.78 TP53 (0.38) TP53DPP4OR51E2
SCHEMBL199977 0.78 TP53 (0.38) TP53DPP4OR51E2
SCHEMBL1406004 0.78 TP53 (0.38) TP53DPP4OR51E2
SCHEMBL16667376 0.78 TP53 (0.38) TP53DPP4OR51E2
SCHEMBL1406003 0.78 TP53 (0.38) TP53DPP4OR51E2
SCHEMBL12778560 0.74
SCHEMBL5482009 0.74
SCHEMBL12779100 0.74
SCHEMBL8969821 0.73 DPP4 (0.33) DPP4OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005005375-A1 METHOD FOR PRODUCING 4-CYANO-3-HYDROXYBUTYRIC ACID ESTERS LANXESS DEUTSCHLAND GMBH (DE) 2005-01-20 WO disclosed