SCHEMBL6234803

SCHEMBL6234803

CCC(C)C(C(=O)O)C(O)CC#N

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CTSS P25774 2/20 0.34
CTSK P43235 1/20 0.34
ALDH1A1 P00352 1/20 0.33
MME P08473 1/20 0.33
ACE P12821 1/20 0.33
CPA1 P15085 1/20 0.33
ACE2 Q9BYF1 1/20 0.33
DPP4 P27487 1/20 0.31
TP53 P04637 1/20 0.31
CTSL P07711 1/20 0.30
CTSB P07858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6234993 0.82 TP53 (0.35) DPP4TP53
SCHEMBL28090209 0.75 ALDH1A1 (0.45) ALDH1A1MMEACECPA1ACE2
SCHEMBL198107 0.75 TDP1 (0.33)
SCHEMBL392365 0.75 TDP1 (0.33)
SCHEMBL10305239 0.75 CHRM1 (0.43) ALDH1A1MMEACECPA1ACE2
SCHEMBL197703 0.75 TDP1 (0.33)
SCHEMBL395419 0.75 TDP1 (0.33)
SCHEMBL1406003 0.74 TP53 (0.38) DPP4TP53
SCHEMBL16667373 0.74 TP53 (0.38) DPP4TP53
SCHEMBL1406004 0.74 TP53 (0.38) DPP4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005005375-A1 METHOD FOR PRODUCING 4-CYANO-3-HYDROXYBUTYRIC ACID ESTERS LANXESS DEUTSCHLAND GMBH (DE) 2005-01-20 WO disclosed