Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185418 | 0.89 | GCK (0.60) | GCKKMT2AALDH1A1LMNAHTT | |
| SCHEMBL623754 | 0.86 | GLA (0.51) | GCKTDP1KMT2AALDH1A1MAPK1 | |
| SCHEMBL184416 | 0.84 | GCK (0.62) | GCKKMT2AALDH1A1MAPK1LMNA | |
| SCHEMBL624697 | 0.80 | GCK (0.50) | GCK | |
| SCHEMBL624577 | 0.79 | GCK (0.49) | GCK | |
| SCHEMBL184745 | 0.77 | GCK (0.58) | GCKKMT2AALDH1A1LMNAHTT | |
| SCHEMBL623036 | 0.76 | GCK (0.79) | GCK | |
| SCHEMBL21881471 | 0.76 | TSHR (0.46) | KMT2AALDH1A1MAPK1LMNAHTT | |
| SCHEMBL21881840 | 0.76 | TSHR (0.46) | KMT2AALDH1A1MAPK1LMNAHTT | |
| SCHEMBL21881480 | 0.76 | TSHR (0.46) | KMT2AALDH1A1MAPK1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020357-A1 | ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS LTD. (IN) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012020357-A1 | ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS LTD. (IN) | 2012-02-16 | — | — | WO | disclosed |