Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GCK | P35557 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184745 | 0.90 | GCK (0.58) | GLAALDH1A1KMT2APKMGCK | |
| SCHEMBL623504 | 0.86 | GCK (0.49) | ALDH1A1KMT2AMAPK1MEN1TDP1 | |
| SCHEMBL11997723 | 0.85 | GCK (0.62) | ALDH1A1KMT2AMAPK1MEN1GCK | |
| SCHEMBL185203 | 0.77 | GLA (0.58) | GLAALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL185418 | 0.77 | GCK (0.60) | GLAALDH1A1KMT2AGCKSMN1; SMN2 | |
| SCHEMBL23349257 | 0.76 | SLC6A3 (0.51) | ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL14068457 | 0.76 | SLC6A3 (0.51) | ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL623545 | 0.76 | GCK (0.55) | GCK | |
| SCHEMBL623036 | 0.76 | GCK (0.79) | GCK | |
| SCHEMBL2653506 | 0.74 | SLC6A3 (0.48) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020357-A1 | ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS LTD. (IN) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012020357-A1 | ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS LTD. (IN) | 2012-02-16 | — | — | WO | disclosed |