SCHEMBL6235611

SCHEMBL6235611

CC1=Cc2c(C(C)C)cccc2C1C[SiH2]c1ccc(C2C(C)=Cc3c(C(C)C)cccc32)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7005222 0.84
SCHEMBL5078341 0.80
SCHEMBL6240510 0.79 GABRA1 (0.33)
SCHEMBL3997056 0.78 GABRA1 (0.33)
SCHEMBL5142617 0.77 CA12 (0.32)
SCHEMBL5080390 0.75 HTR2A (0.33)
SCHEMBL7031598 0.74 GABRA1 (0.36)
SCHEMBL4005260 0.74 HTR2A (0.32)
SCHEMBL7107423 0.72 GABRA1 (0.34)
SCHEMBL8057411 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6143686-A FOR ADDITION POLYMERIZATION OF ALPHA OLEFINS, SUCH AS PROPYLENE TO PRODUCE STEREOSPECIFIC POLMER EXXON CHEMICAL PATENTS, INC. (US) 2000-11-07 US claimed
US-5914376-A Catalyst for the polymerization of olefins, process for the preparation thereof, and use thereof TARGOR GMBH (DE) 1999-06-22 US claimed
WO-2005003184-A1 POLYMERIZATION PROCESSES USING ANTISTATIC AGENTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-01-13 WO disclosed
EP-1373337-A2 PROPYLENE POLYMERS FOR FILMS Exxonmobil Chemical Patents Inc. (US) 2004-01-02 EP disclosed
EP-1313782-A1 POLYPROPYLENE POLYMERS Exxonmobil Chemical Patents Inc. (US) 2003-05-28 EP disclosed
EP-1263909-A2 POLYPROPYLENE-BASED ADHESIVE COMPOSITIONS ExxonMobil Chemical Patents Inc. (US) 2002-12-11 EP disclosed
EP-0773204-B1 Process for the preparation of an indene and use thereof for the preparation of metallocenes BASELL POLYOLEFINE GMBH (DE) 2002-12-04 EP disclosed
WO-2002070572-A2 PROPYLENE POLYMERS FOR FILMS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-09-12 WO disclosed
WO-2002070570-A2 PROPYLENE POLYMERS FOR FILMS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-09-12 WO disclosed
WO-2002016455-A1 POLYPROPYLENE POLYMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-02-28 WO disclosed
WO-2001046277-A2 POLYPROPYLENE-BASED ADHESIVE COMPOSITIONS EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2001-06-28 WO disclosed
US-6143686-A FOR ADDITION POLYMERIZATION OF ALPHA OLEFINS, SUCH AS PROPYLENE TO PRODUCE STEREOSPECIFIC POLMER EXXON CHEMICAL PATENTS, INC. (US) 2000-11-07 US disclosed
EP-0530647-B1 Metallocenes, catalysts containing these and process for the manufacture of olefinic polymers by using these catalysts HOECHST AG (DE) 1998-01-28 EP disclosed
EP-0773204-A2 Process for the preparation of an indene and use thereof for the preparation of metallocenes HOECHST AKTIENGESELLSCHAFT (DE) 1997-05-14 EP disclosed
US-5278264-A Catalytic polymerizing in presence of a transition metal metallocene HOECHST AG (DE) 1994-01-11 US disclosed
EP-0530647-A1 Metallocenes, catalysts containing these and process for the manufacture of olefinic polymers by using these catalysts HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-10 EP disclosed