Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5080390 | 0.99 | HTR2A (0.33) | HTR2A | |
| SCHEMBL4006148 | 0.82 | MEN1 (0.33) | — | |
| SCHEMBL5080422 | 0.81 | MEN1 (0.34) | — | |
| SCHEMBL4006186 | 0.76 | HTR2A (0.37) | HTR2A | |
| SCHEMBL5078341 | 0.75 | — | — | |
| SCHEMBL1241035 | 0.74 | HTR2A (0.38) | HTR2A | |
| SCHEMBL6673270 | 0.74 | GAA (0.35) | HTR2A | |
| SCHEMBL6235611 | 0.74 | — | — | |
| SCHEMBL5142617 | 0.73 | CA12 (0.32) | — | |
| SCHEMBL28055090 | 0.71 | KDM1A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556417-B1 | RACEMOSELECTIVE PREPARATION OF BRIDGED METALLOCENE COMPLEXES HAVING UNSUBSTITUTED OR 2-SUBSTITUTED INDENYL LIGANDS | BASELL POLYOLEFINE GMBH (DE) | 2009-06-10 | — | — | EP | disclosed |
| EP-1554296-B1 | RACEMOSELECTIVE PREPARATION OF ISOLABLE ANSA-METALLOCENE BIPHENOXIDE COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2008-10-15 | — | — | EP | disclosed |
| US-7358381-B2 | Racemoselective preparation of bridged metallocene complexes having unsubstituted or 2-substituted indenyl ligands | BASELL POLYOLEFINE GMBH (DE) | 2008-04-15 | — | — | US | disclosed |
| US-7193099-B2 | Racemoselective preparation of isolable ansa-metallocene biphenoxide complexes | BASELL POLYOLEFINE GMBH (DE) | 2007-03-20 | — | — | US | disclosed |
| US-20060111527-A1 | Racemoselective preparation of bridged metallocene complexes having unsubstituted or 2-substituted indenyl ligands | EQUISTAR CHEMICALS, LP | 2006-05-25 | — | — | US | disclosed |
| US-20060052587-A1 | Racemoselective preparation of isolable ansa-metallocene biphenoxide complexes | BASELL POLYOLEFINE GMBH (DE) | 2006-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111527-A1 | Racemoselective preparation of bridged metallocene complexes having unsubstituted or 2-substituted indenyl ligands | ITPA, IMPA1, INTS9 | HTR2A 3754/4885 |
| US-20060052587-A1 | Racemoselective preparation of isolable ansa-metallocene biphenoxide complexes | ITPA, NBAS, ARSA | HTR2A 3203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.