Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | FADS1 | O60427 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233510 | 0.91 | MAPK14 (0.41) | NPY5RACP1MEN1KMT2AMAPT | |
| SCHEMBL6231257 | 0.91 | MEN1 (0.42) | NPY5RACP1MEN1KMT2AMAPT | |
| SCHEMBL6235371 | 0.91 | MAPT (0.42) | NPY5RACP1MEN1KMT2AMAPT | |
| SCHEMBL6235120 | 0.91 | NPY5R (0.47) | NPY5RACP1MEN1KMT2AMAPT | |
| SCHEMBL6235953 | 0.88 | ACP1 (0.43) | ACP1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL6234079 | 0.87 | SLC2A1 (0.50) | NPY5RACP1MEN1KMT2AMAPT | |
| SCHEMBL6089017 | 0.84 | POLA1 (0.43) | NPY5RACP1MEN1KMT2AMAPT | |
| SCHEMBL6088154 | 0.81 | SLC2A1 (0.40) | NPY5RACP1MEN1KMT2AMAPT | |
| SCHEMBL6229818 | 0.81 | CCNC (0.48) | NPY5RACP1MEN1KMT2AMAPT | |
| SCHEMBL6351009 | 0.80 | MEN1 (0.54) | MEN1KMT2AMAPTATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430030-B1 | N-TYPE CALCIUM CHANNEL ANTAGONISTS FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2005-05-18 | — | — | EP | disclosed |