Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235697 | 0.88 | NPY5R (0.39) | ACP1KDRSMN1; SMN2TP53MAPT | |
| SCHEMBL6232210 | 0.88 | MAPT (0.45) | ACP1SMN1; SMN2TP53MAPTNPC1 | |
| SCHEMBL6231257 | 0.84 | MEN1 (0.42) | ACP1SMN1; SMN2TP53MAPTNPC1 | |
| SCHEMBL6233510 | 0.84 | MAPK14 (0.41) | ACP1SMN1; SMN2TP53MAPTRAB9A | |
| SCHEMBL6233225 | 0.84 | POLB (0.51) | ACP1SMN1; SMN2TP53MAPTNPC1 | |
| SCHEMBL6235120 | 0.84 | NPY5R (0.47) | ACP1SMN1; SMN2TP53MAPTKMT2A | |
| SCHEMBL6235371 | 0.80 | MAPT (0.42) | ACP1SMN1; SMN2TP53MAPTGAA | |
| SCHEMBL6236871 | 0.78 | SMN1; SMN2 (0.66) | ACP1SMN1; SMN2TP53MAPTNPC1 | |
| SCHEMBL6231880 | 0.78 | THRB (0.55) | ACP1ERBB2EPHA2KDRSMN1; SMN2 | |
| SCHEMBL6089017 | 0.78 | POLA1 (0.43) | ACP1ERBB2EPHA2KDRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430030-B1 | N-TYPE CALCIUM CHANNEL ANTAGONISTS FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2005-05-18 | — | — | EP | disclosed |