Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 16/20 | 0.63 |
| ▸ | PIM1 | P11309 | 3/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623846 | 0.88 | FYN (0.57) | FYNPIM1MKNK1 | |
| SCHEMBL625204 | 0.87 | FYN (0.60) | FYNPIM1MKNK1 | |
| SCHEMBL624030 | 0.87 | FYN (0.59) | FYNPIM1MKNK1 | |
| SCHEMBL17004609 | 0.86 | FYN (0.67) | FYNPIM1MKNK1 | |
| SCHEMBL623578 | 0.83 | F2RL3 (0.48) | FYNPIM1 | |
| SCHEMBL628028 | 0.83 | FYN (0.56) | FYNPIM1MKNK1 | |
| SCHEMBL623881 | 0.83 | FYN (0.60) | FYNPIM1MKNK1 | |
| SCHEMBL1946065 | 0.82 | FYN (0.68) | FYNPIM1MKNK1 | |
| SCHEMBL1946037 | 0.78 | FYN (1.00) | FYNPIM1MKNK1 | |
| SCHEMBL2257604 | 0.76 | MKNK1 (0.77) | FYNPIM1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |