Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 9/20 | 0.59 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 9/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17004609 | 0.93 | FYN (0.67) | FYNMKNK1PIM1KCNH2PIM3 | |
| SCHEMBL623846 | 0.91 | FYN (0.57) | FYNMKNK1PIM1KCNH2PIM3 | |
| SCHEMBL623881 | 0.87 | FYN (0.60) | FYNMKNK1PIM1KCNH2PIM3 | |
| SCHEMBL623577 | 0.87 | FYN (0.63) | FYNMKNK1PIM1 | |
| SCHEMBL1946065 | 0.86 | FYN (0.68) | FYNMKNK1PIM1KCNH2PIM2 | |
| SCHEMBL625204 | 0.86 | FYN (0.60) | FYNMKNK1PIM1PIM3PIM2 | |
| SCHEMBL628028 | 0.82 | FYN (0.56) | FYNMKNK1PIM1KCNH2PIM3 | |
| SCHEMBL2257604 | 0.81 | MKNK1 (0.77) | FYNMKNK1PIM1 | |
| SCHEMBL624031 | 0.81 | F2RL3 (0.50) | FYNPIM1CHRM4PIM2 | |
| SCHEMBL1947242 | 0.80 | FYN (0.71) | FYNMKNK1PIM1KCNH2PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |