SCHEMBL6236037

SCHEMBL6236037

Cc1cnc(C(C)NCc2ccc(OCc3cccc(C#N)c3)cc2)s1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.45
FFAR1 O14842 2/20 0.44
FFAR4 Q5NUL3 1/20 0.44
CYP4F2 P78329 1/20 0.42
CYP4A11 Q02928 1/20 0.42
ADAMTS4 O75173 1/20 0.42
MMP13 P45452 1/20 0.42
MAOA P21397 1/20 0.41
SCN9A Q15858 1/20 0.41
CTSA P10619 1/20 0.41
CD274 Q9NZQ7 4/20 0.40
PDCD1 Q15116 3/20 0.40
GRM5 P41594 1/20 0.40
BCHE P06276 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6236034 1.00 MAOB (0.45) MAOBFFAR1FFAR4CYP4F2CYP4A11
SCHEMBL6237847 0.85 BCHE (0.54) BCHE
SCHEMBL6237852 0.85 BCHE (0.54) BCHE
SCHEMBL6233012 0.77 CASR (0.49) CTSA
SCHEMBL6255976 0.77 CASR (0.49) CTSA
SCHEMBL6235475 0.74 MTNR1A (0.46) CTSA
SCHEMBL6276107 0.74 MTNR1A (0.46) CTSA
SCHEMBL1071923 0.74 MAOB (0.72) MAOBFFAR1FFAR4MAOASCN9A
SCHEMBL6234535 0.73 BCHE (0.50) BCHE
SCHEMBL6255029 0.73 BCHE (0.50) BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005000309-A2 CHEMICAL COMPOUNDS IONIX PHARMACEUTICALS LIMITED (GB) 2005-01-06 WO disclosed