Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CTSA | P10619 | 2/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6276107 | 1.00 | MTNR1A (0.46) | MTNR1AMTNR1BABCB1NPC1RAB9A | |
| SCHEMBL6231706 | 0.90 | LMNA (0.53) | NPC1RAB9ASMARCA2LMNAHTR1A | |
| SCHEMBL6231703 | 0.90 | LMNA (0.53) | NPC1RAB9ASMARCA2LMNAHTR1A | |
| SCHEMBL6236884 | 0.85 | SMN1; SMN2 (0.46) | NPC1RAB9ACTSALMNAHTT | |
| SCHEMBL6232051 | 0.81 | MEN1 (0.51) | LMNAHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL6230153 | 0.81 | MEN1 (0.51) | LMNAHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL6236909 | 0.80 | NTRK1 (0.41) | NPC1RAB9ACTSACSF1RLMNA | |
| SCHEMBL6233814 | 0.80 | FFAR4 (0.45) | RAB9ACTSALMNASLC2A1ALDH1A1 | |
| SCHEMBL6235977 | 0.79 | KMT2A (0.57) | CTSALMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL6235480 | 0.79 | BCHE (0.53) | MTNR1AMTNR1BABCB1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |