Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CCR6 | P51684 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236215 | 1.00 | MAPT (0.60) | MAPTKMT2APKMMEN1NPC1 | |
| SCHEMBL6243666 | 0.92 | MAPT (0.54) | MAPTKMT2APKMMEN1NPC1 | |
| SCHEMBL6243664 | 0.92 | MAPT (0.54) | MAPTKMT2APKMMEN1NPC1 | |
| SCHEMBL845971 | 0.84 | CA12 (0.65) | MAPTKMT2APKMMEN1MAOB | |
| SCHEMBL13957414 | 0.84 | CA12 (0.65) | MAPTKMT2APKMMEN1MAOB | |
| SCHEMBL275824 | 0.84 | CA12 (0.65) | MAPTKMT2APKMMEN1MAOB | |
| SCHEMBL15347690 | 0.81 | KMT2A (0.64) | MAPTKMT2APKMMEN1NPC1 | |
| SCHEMBL6236523 | 0.81 | GLO1 (0.50) | MAPTKMT2APKMMEN1NPC1 | |
| SCHEMBL6236528 | 0.81 | GLO1 (0.50) | MAPTKMT2APKMMEN1NPC1 | |
| SCHEMBL11980044 | 0.81 | KMT2A (0.48) | MAPTKMT2APKMMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011661-A1 | PHARMACEUTICAL AGENTS | UNIVERSITY COLLEGE LONDON (GB) | 2005-02-10 | — | — | WO | disclosed |