Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236528 | 1.00 | GLO1 (0.50) | GLO1KMT2AMEN1LMNAMAPT | |
| SCHEMBL3034226 | 0.89 | GLO1 (0.54) | GLO1KMT2AMEN1LMNAMAPT | |
| SCHEMBL3034223 | 0.89 | GLO1 (0.54) | GLO1KMT2AMEN1LMNAMAPT | |
| SCHEMBL1856657 | 0.82 | GLO1 (0.66) | GLO1KMT2AMEN1LMNAMAPT | |
| SCHEMBL9296584 | 0.81 | GLO1 (0.73) | GLO1KMT2AMEN1LMNAMAPT | |
| SCHEMBL28627286 | 0.81 | MAOB (0.50) | GLO1KMT2AMEN1LMNAMAPT | |
| SCHEMBL9296374 | 0.81 | GLO1 (0.73) | GLO1KMT2AMEN1LMNAMAPT | |
| SCHEMBL6236217 | 0.81 | MAPT (0.60) | GLO1KMT2AMEN1LMNAMAPT | |
| SCHEMBL9296381 | 0.81 | GLO1 (0.73) | GLO1KMT2AMEN1LMNAMAPT | |
| SCHEMBL6236215 | 0.81 | MAPT (0.60) | GLO1KMT2AMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011661-A1 | PHARMACEUTICAL AGENTS | UNIVERSITY COLLEGE LONDON (GB) | 2005-02-10 | — | — | WO | disclosed |