Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | CALML3 | P27482 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | SDHA | P31040 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210340 | 1.00 | MAOA (0.45) | MAOACYP3A4CYP2D6MAOBCALML3 | |
| SCHEMBL6243076 | 0.91 | CYP3A4 (0.42) | MAOACYP3A4CYP2D6CALML3F10 | |
| SCHEMBL6243081 | 0.91 | CYP3A4 (0.42) | MAOACYP3A4CYP2D6CALML3F10 | |
| SCHEMBL6242292 | 0.89 | MAOA (0.45) | MAOACYP3A4CYP2D6MAOBCALML3 | |
| SCHEMBL6242288 | 0.89 | MAOA (0.45) | MAOACYP3A4CYP2D6MAOBCALML3 | |
| SCHEMBL6237819 | 0.85 | MAOA (0.51) | MAOAMAOBCALML3PTGS1SDHA | |
| SCHEMBL6237827 | 0.85 | MAOA (0.51) | MAOAMAOBCALML3PTGS1SDHA | |
| SCHEMBL6243306 | 0.84 | MAOA (0.51) | MAOAMAOBCALML3PTGS1SDHA | |
| SCHEMBL6243297 | 0.84 | MAOA (0.51) | MAOAMAOBCALML3PTGS1SDHA | |
| SCHEMBL6240231 | 0.81 | MAOA (0.46) | MAOAMAOBCALML3PTGS1SDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288273-A1 | Antibacterial agents | BOYER FREDERICK E JR | 2005-12-29 | — | — | US | disclosed |
| EP-1594865-A2 | ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004069832-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2004-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288273-A1 | Antibacterial agents | MRPL21, RPN2, FBL | MAOA 236/4885CYP3A4 815/4885CYP2D6 134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.