Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 6/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.36 |
| ▸ | RPS27 | P42677 | 3/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.32 |
| ▸ | CTSB | P07858 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL617783 | 0.74 | MAPK8 (0.40) | MAPK8MAPK9RPS27MAPK10FNTA | |
| SCHEMBL621914 | 0.73 | MAPK8 (0.39) | MAPK8MAPK9RPS27MAPK10FNTA | |
| SCHEMBL15665534 | 0.63 | KMT2A (0.39) | MAPK8MAPK9RPS27MAPK10MEN1 | |
| SCHEMBL15665537 | 0.63 | KMT2A (0.39) | MAPK8MAPK9RPS27MAPK10MEN1 | |
| SCHEMBL15666129 | 0.63 | KMT2A (0.39) | MAPK8MAPK9RPS27MAPK10MEN1 | |
| SCHEMBL28457030 | 0.62 | KMT2A (0.40) | MAPK8MAPK9RPS27MAPK10FNTA | |
| SCHEMBL31670289 | 0.60 | CTSS (0.48) | CTSLCTSBCTSSCTSK | |
| SCHEMBL9493658 | 0.59 | CALM1 (0.55) | TSHRHSD17B10 | |
| SCHEMBL1681134 | 0.58 | MAOB (0.44) | FNTAFNTBMEN1TSHRKMT2A | |
| Diphenylmethane SCHEMBL28095916 | 0.58 | ALPI (0.55) | ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603098-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | Senomyx, Inc. (US) | 2013-06-19 | — | — | EP | disclosed |
| WO-2012021837-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | WO | disclosed |