Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9414595 | 0.85 | KMT2A (0.54) | LMNAATMNPSR1POLBALDH1A1 | |
| SCHEMBL9675030 | 0.85 | PARP1 (0.53) | LMNAATMNPSR1POLBALDH1A1 | |
| SCHEMBL1542104 | 0.82 | SMN1; SMN2 (0.55) | LMNAATMNPSR1POLBALDH1A1 | |
| SCHEMBL1563249 | 0.81 | KDM4E (0.50) | ALDH1A1SMN1; SMN2CYP1A2KDM4EMAPK1 | |
| SCHEMBL8767256 | 0.80 | SMN1; SMN2 (0.57) | LMNANPSR1POLBALDH1A1L3MBTL1 | |
| SCHEMBL28917493 | 0.77 | SMN1; SMN2 (0.50) | LMNAPOLBALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9044915 | 0.77 | KDM4E (0.53) | LMNAATMALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL8213702 | 0.77 | PDE4A (0.54) | LMNAATMNPSR1POLBALDH1A1 | |
| SCHEMBL2446205 | 0.73 | KDM4E (0.65) | LMNAATMNPSR1POLBALDH1A1 | |
| SCHEMBL3317724 | 0.72 | POLB (0.55) | LMNAATMNPSR1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532149-A2 | 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THE PRODUCTION THEREOF AND THE USE OF THE SAME AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004018468-A2 | 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THE PRODUCTION THEREOF AND THE USE OF THE SAME AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-03-04 | — | — | WO | disclosed |