Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304472 | 0.81 | — | — | |
| SCHEMBL13668738 | 0.69 | — | — | |
| SCHEMBL2233762 | 0.69 | — | — | |
| SCHEMBL13337384 | 0.67 | — | — | |
| SCHEMBL10924835 | 0.67 | — | — | |
| SCHEMBL22654548 | 0.67 | CDC25A (0.38) | TSHRALOX15TDP1ALDH1A1 | |
| SCHEMBL2051403 | 0.59 | ALDH1A1 (0.36) | TSHRALDH1A1 | |
| SCHEMBL3292856 | 0.59 | CDC25A (0.33) | — | |
| SCHEMBL8625019 | 0.57 | — | — | |
| SCHEMBL194752 | 0.53 | TSHR (1.00) | TSHRALOX15TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016260-A2 | PRODRUGS FOR THE ORAL AND PARENTERAL DELIVERY OF AMINE-CONTAINING DRUGS, AMINO ACIDS, AND PEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-02-24 | — | — | WO | disclosed |