⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236482 | 0.81 | TSHR (0.36) | — | |
| SCHEMBL3292856 | 0.77 | CDC25A (0.33) | — | |
| SCHEMBL304729 | 0.75 | ALDH1A1 (0.33) | — | |
| SCHEMBL15268000 | 0.75 | CDC25A (0.40) | — | |
| SCHEMBL1165248 | 0.73 | CDC25A (0.47) | — | |
| SCHEMBL24925115 | 0.71 | — | — | |
| SCHEMBL8134293 | 0.71 | IDO1 (0.32) | — | |
| SCHEMBL138955 | 0.71 | — | — | |
| SCHEMBL22654547 | 0.71 | ALOX15 (0.37) | — | |
| SCHEMBL1164743 | 0.70 | CDC25A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4526986-A | Reacting dimethyl maleic anhydride with bromotrichloro methane in the presence of actinic radiation | STANDARD OIL COMPANY (INDIANA) (US) | 1985-07-02 | — | — | US | claimed |
| US-20230158005-A1 | Substituted Azole Dione Compounds with Antiviral Activity | STEMLINE THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230158005-A1 | Substituted Azole Dione Compounds with Antiviral Activity | STEMLINE THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| EP-3567035-B1 | N-SUBSTITUTED 2,5-DIOXO-AZOLINE COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | CANBAS CO LTD (JP) | 2022-06-01 | — | — | EP | disclosed |
| EP-3567035-A1 | N-SUBSTITUTED 2,5-DIOXO-AZOLINE COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | Canbas Co. Ltd. (JP) | 2019-11-13 | — | — | EP | disclosed |
| EP-1506218-B1 | REVERSIBLE MODIFICATION OF MEMBRANE INTERACTION | ARROWHEAD PHARMACEUTICALS INC (US) | 2017-04-12 | — | — | EP | disclosed |
| EP-3088397-A1 | COMPOUNDS THAT ABROGATE THE CELL CYCLE G2 CHECKPOINT FOR USE IN THE TREATMENT OF CANCER | Canbas Co. Ltd. (JP) | 2016-11-02 | — | — | EP | disclosed |
| EP-2152692-B1 | COMPOUNDS WITH ANTI-CANCER ACTIVITY | CANBAS CO LTD (JP) | 2016-06-15 | — | — | EP | disclosed |
| US-20160151322-A1 | METALLO-B-LACTAMASE INHIBITORS | MEIJI SEIKA KAISHA (JP) | 2016-06-02 | — | — | US | disclosed |
| US-9260375-B2 | Metallo-β-lactamase inhibitors | MEIJI SEIKA KAISHA, LTD. (JP) | 2016-02-16 | — | — | US | disclosed |
| EP-1941873-A1 | METALLO-BETA-LACTAMASE INHIBITOR | MEIJI SEIKA KAISHA LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| US-20080090825-A1 | Metallo-beta-lactamase inhibitors | MEIJI SEIKA KAISHA, LTD. (JP) | 2008-04-17 | — | — | US | disclosed |
| US-20060122096-A1 | Reversible modification of amine-containing compounds | Arrowhead Madison Inc. | 2006-06-08 | — | — | US | disclosed |
| US-7019113-B2 | Reversible modification of membrane interaction | MIRUS BIO CORPORATION (US) | 2006-03-28 | — | — | US | disclosed |
| US-20050250683-A9 | Reversible modification of membrane interaction | Arrowhead Madison Inc. | 2005-11-10 | — | — | US | disclosed |
| EP-1506218-A2 | REVERSIBLE MODIFICATION OF MEMBRANE INTERACTION | Mirus Corporation (US) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003100081-A2 | BIOLOGICALLY ACTIVE MALEAMIC ACID DERIVATIVES WITH LABILE AMIDE BONDS | MIRUS CORPORATION (US) | 2003-12-04 | — | — | WO | disclosed |
| US-20030220264-A1 | Reversible modification of membrane interaction | ROZEMA DAVID B (US) | 2003-11-27 | — | — | US | disclosed |
| US-4560761-A | SURFACTANTS, MICROBIOCIDES, HYDRAULIC FLUIDS | STANDARD OIL COMPANY (INDIANA) (US) | 1985-12-24 | — | — | US | disclosed |
| US-4526986-A | Reacting dimethyl maleic anhydride with bromotrichloro methane in the presence of actinic radiation | STANDARD OIL COMPANY (INDIANA) (US) | 1985-07-02 | — | — | US | disclosed |