Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 4/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28002633 | 0.95 | BBOX1 (0.42) | BBOX1KMT2AATMALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL623653 | 0.90 | BBOX1 (0.47) | BBOX1KMT2AATMALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL27783045 | 0.88 | BBOX1 (0.46) | BBOX1KMT2AATMALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL28743750 | 0.88 | BBOX1 (0.41) | BBOX1KMT2AATMALDH1A1 | |
| SCHEMBL27653675 | 0.86 | BBOX1 (0.40) | BBOX1KMT2AATMALDH1A1ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL1171567 | 0.84 | BBOX1 (0.39) | BBOX1KMT2AATMALDH1A1ACHE | |
| Sulfuric Acid SCHEMBL434070 | 0.84 | BBOX1 (0.45) | BBOX1KMT2AATMALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL10901760 | 0.84 | TSHR (0.39) | BBOX1TSHRACHEBLMBCHE | |
| Sulfuric Acid SCHEMBL22320251 | 0.84 | BBOX1 (0.36) | BBOX1ACHEBCHECA5ACA5B | |
| SCHEMBL33742 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 420 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2109441-B1 | POLYSILOXANE BLOCK COPOLYMERS | BASF SE (DE) | 2016-01-27 | — | — | EP | claimed |
| US-8378038-B2 | Polysiloxane block copolymers | BASF SE (DE) | 2013-02-19 | — | — | US | claimed |
| EP-1841506-B1 | THE USE OF HIGH MOLECULAR WEIGHT CROSSLINKED, WATER-SOLUBLE CATIONIC POLYMERS IN HAIR CARE FORMULATIONS | BASF SE (DE) | 2012-04-25 | — | — | EP | claimed |
| US-7964669-B2 | Temporary wet strength resin for paper applications | KEMIRA OYJ (FI) | 2011-06-21 | — | — | US | claimed |
| US-7872083-B2 | Polymer and cosmetic preparation | SHISEIDO CO., LTD. (JP) | 2011-01-18 | — | — | US | claimed |
| US-20100303750-A1 | POLYSILOXANE BLOCK COPOLYMERS | KOROSKENYI BALINT | 2010-12-02 | — | — | US | claimed |
| US-20100190948-A1 | TEMPORARY WET STRENGTH RESIN FOR PAPER APPLICATIONS | PROVERB ROBERT JOSEPH | 2010-07-29 | — | — | US | claimed |
| CN-1965036-B | Novel dry mineral pigments containing calcium carbonate, aqueous suspensions containing same and use thereof | OMYA DEVELOPMENT AG | 2010-06-23 | — | — | CN | claimed |
| JP-2009545641-A | — | — | 2009-12-24 | — | — | JP | claimed |
| CN-100558771-C | Copolymer having at least one alkoxy-or hydroxy-polyalkylene glycol graft function and use thereof | OMYA AG (CH) | 2009-11-11 | — | — | CN | claimed |
| EP-1539827-A1 | HIGH MOLECULAR WEIGHT CATIONIC POLYMERS OBTAINED BY POST-POLYMERISATION CROSSLINKING REACTION | Ciba Specialty Chemicals Water Treatments Limited (GB) | 2005-06-15 | — | — | EP | claimed |
| WO-2004101882-A1 | USE OF WATER-SOLUBLE CROSSLINKED CATIONIC POLYMERS FOR CONTROLLING DEPOSITION OF PITCH AND STICKIES IN PAPERMAKING | CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) | 2004-11-25 | — | — | WO | claimed |
| US-20040226676-A1 | Use of water-soluble crosslinked cationic polymers for controlling deposition of pitch and stickies in papermaking | CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) | 2004-11-18 | — | — | US | claimed |
| WO-2004018524-A1 | HIGH MOLECULAR WEIGHT CATIONIC POLYMERS OBTAINED BY POST-POLYMERISATION CROSSLINKING REACTION | CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) | 2004-03-04 | — | — | WO | claimed |
| US-20040034156-A1 | High molecular weight cationic polymers obtained by post-polymerization crosslinking reaction | CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) | 2004-02-19 | — | — | US | claimed |
| US-6207771-B1 | INCREMENTAL ADDITION OF A HYDROPHOBIC MONOMER TO A REACTION MEDIUM WHICH INCLUDES BOTH A WATER SOLUBLE MONOMER AND A SURFACE ACTIVE AGENT, SO THAT HYDROPHOBIC MONOMER IS PRESENT IN A CONSTANT CONCENTRATION THROUHOUT THE POLYMERIZATION | RHODIA CHIMIE (FR) | 2001-03-27 | — | — | US | claimed |
| US-6206935-B1 | APPLYING BLEACHING AGENTS AND DIRECT DYE | KAO CORPORATION (JP) | 2001-03-27 | — | — | US | claimed |
| US-6127494-A | INCREMENTAL ADDITION OF A HYDROPHOBIC MONOMER TO A REACTION MEDIUM WHICH INCLUDES BOTH A WATER SOLUBLE MONOMER AND A SURFACE ACTIVE AGENT, SO THAT HYDROPHOBIC MONMER IS PRESENT IN A CONSTANT CONCENTRATION THROUGHOUT THE POLYMERIZATION | RHODIA CHIMIE (FR) | 2000-10-03 | — | — | US | claimed |
| EP-0996644-A1 | METHOD FOR PRODUCING POLYMERS USING MICELLAR POLYMERIZATION | RHODIA CHIMIE (FR) | 2000-05-03 | — | — | EP | claimed |
| WO-1999003895-A1 | METHOD FOR PRODUCING POLYMERS USING MICELLAR POLYMERIZATION | RHODIA CHIMIE (FR) | 1999-01-28 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100303750-A1 | POLYSILOXANE BLOCK COPOLYMERS | KRT18, PUF60, SCNN1B | BBOX1 2288/4885KMT2A 429/4885ATM 3967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.