SCHEMBL623664

SCHEMBL623664

C1CCC2CCCC(C1)CCC2

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
THRB P10828 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TSHR P16473 1/20 0.36
ADH1A P07327 3/20 0.32
ADH1C P00326 2/20 0.32
HSD17B10 Q99714 1/20 0.31
ADH4 P08319 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22129576 1.00 ALDH1A1 (0.42) ALDH1A1THRBMEN1KMT2ATSHR
SCHEMBL22129635 0.95 ALDH1A1 (0.39) ALDH1A1THRBMEN1KMT2ATSHR
SCHEMBL138183 0.95 ALDH1A1 (0.39) ALDH1A1THRBMEN1KMT2ATSHR
SCHEMBL499430 0.94 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL893278 0.91 ALDH1A1 (0.36) ALDH1A1THRBMEN1KMT2ATSHR
SCHEMBL22129587 0.89 ALDH1A1 (0.42) ALDH1A1THRBMEN1KMT2ATSHR
SCHEMBL10435134 0.89 ALDH1A1 (0.31) ALDH1A1
SCHEMBL359932 0.89 ALDH1A1 (0.31) ALDH1A1
SCHEMBL27392 0.89
SCHEMBL893491 0.89 ALDH1A1 (0.42) ALDH1A1THRBMEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4417180-A2 THERMO-ACTIVE COMPOSITE DENTAL COMPOSITION VOCO GmbH (DE) 2024-08-21 EP claimed
EP-3810064-B1 THERMOACTIVE DENTAL COMPOSITE COMPOSITION VOCO GMBH (DE) 2024-05-29 EP claimed
US-11944692-B2 Thermoactive dental composite composition VOCO GMBH (DE) 2024-04-02 US claimed
EP-3810064-A1 THERMOACTIVE DENTAL COMPOSITE COMPOSITION VOCO GmbH (DE) 2021-04-28 EP claimed
WO-2019243339-A1 THERMOACTIVE DENTAL COMPOSITE COMPOSITION VOCO GMBH (DE) 2019-12-26 WO claimed
EP-1657239-B1 Chromene compound TOKUYAMA CORP (JP) 2010-08-11 EP claimed
WO-2026103730-A1 DIAZAHETEROCYCLIC DERIVATIVE OF PYRIDOARYL GROUP HAVING KAPPA RECEPTOR ANTAGONISTIC ACTIVITY AND COMPOSITION THEREOF, AND USE 江苏恩华药业股份有限公司 2026-05-21 WO disclosed
WO-2026090589-A1 HETEROCYCLIC HBS1L DEGRADERS TANGO THERAPEUTICS, INC. (US) 2026-04-30 WO disclosed
US-12612424-B2 HPK1 inhibitors and uses thereof REGOR PHARMACEUTICALS, INC. (US) 2026-04-28 US disclosed
US-20260078117-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS INC (US) 2026-03-19 US disclosed
US-20260070917-A1 CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF DIFFERENTIATED THERAPEUTICS INC (US) 2026-03-12 US disclosed
US-20260062426-A1 CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF DIFFERENTIATED THERAPEUTICS INC (US) 2026-03-05 US disclosed
EP-4673449-A1 CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF Differentiated Therapeutics Inc (US) 2026-01-07 EP disclosed
US-20050112409-A1 Magnetic recording medium FUJI PHOTO FILM CO., LTD. 2005-05-26 US disclosed
US-20040094753-A1 Chromene compound TOKUYAMA CORPORATION (JP) 2004-05-20 US disclosed
US-6723859-B2 BASE STRUCTURE IS A CHROMENE(3,2-A)FLUORENE RING CONTAINING SPIRO-FUSED RINGS; PHOTOCHROMIC LENSES; LARGE FADING RATE, LESS COLOR WHEN DETERIORATED, AND EXCELLENT LIGHT RESISTANCE IN THE PHOTOCHROMIC PROPERTIES TOKUYAMA CORPORATION (JP) 2004-04-20 US disclosed
EP-1394156-A1 CHROMENE COMPOUND TOKUYAMA CORPORATION (JP) 2004-03-03 EP disclosed
US-20040014995-A1 Chromene compounds KAWABATA YUICHIRO (JP) 2004-01-22 US disclosed
US-20030096117-A1 Chromene compound TOKUYAMA CORPORATION (JP) 2003-05-22 US disclosed
EP-1184379-A1 CHROMENE COMPOUND TOKUYAMA CORPORATION (JP) 2002-03-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612424-B2 HPK1 inhibitors and uses thereof NEK11, NEK1, CSNK1A1 ALDH1A1 3619/4885THRB 953/4885MEN1 3442/4885
US-20040014995-A1 Chromene compounds SMARCE1, SMARCB1, SMARCA2 ALDH1A1 2905/4885THRB 4750/4885MEN1 2481/4885
US-20260062426-A1 CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF CCNA1, CCNE1, CCNA2 ALDH1A1 1035/4885THRB 964/4885MEN1 3740/4885
US-20260078117-A1 COMPOUNDS AND METHODS OF USE NR3C2, ADRA1A, CNR1 ALDH1A1 100/4885THRB 995/4885MEN1 1978/4885
US-20260070917-A1 CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF CDK2, CCNK, CCNC ALDH1A1 2041/4885THRB 2558/4885MEN1 3638/4885
US-20030096117-A1 Chromene compound SMARCE1, SMARCD2, SMARCB1 ALDH1A1 3101/4885THRB 4732/4885MEN1 2413/4885
US-11944692-B2 Thermoactive dental composite composition PUF60, POLQ, F10 ALDH1A1 1414/4885THRB 4503/4885MEN1 1542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.