Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 18/20 | 0.88 |
| ▸ | HMGCR | P04035 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233280 | 0.90 | ALOX5 (0.77) | ALOX5HMGCRMAPK1PTGS2 | |
| SCHEMBL27868551 | 0.81 | ALOX5 (0.73) | ALOX5HMGCRPTGS2 | |
| SCHEMBL6236706 | 0.79 | ALOX5 (0.58) | ALOX5 | |
| SCHEMBL18029847 | 0.79 | ALOX5 (0.75) | ALOX5PTGS2 | |
| SCHEMBL6231507 | 0.79 | ALOX5 (0.57) | ALOX5NPC1HPGDMAPK1HTT | |
| SCHEMBL6233136 | 0.79 | ALOX5 (0.57) | ALOX5NPC1HPGDMAPK1HTT | |
| SCHEMBL5588414 | 0.78 | ALOX5 (0.54) | ALOX5NPC1HPGDMAPK1HTT | |
| SCHEMBL6233674 | 0.78 | ALOX5 (0.56) | ALOX5NPC1HPGDMAPK1HTT | |
| SCHEMBL515721 | 0.76 | ALOX5 (0.57) | ALOX5NPC1HPGDMAPK1HTT | |
| SCHEMBL9578675 | 0.76 | ALOX5 (0.88) | ALOX5HMGCRPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |