Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233136 | 0.95 | ALOX5 (0.57) | ALOX5NPC1HPGDMAPK1HTT | |
| SCHEMBL6232977 | 0.90 | ALOX5 (0.48) | ALOX5LTB4RMEN1KMT2A | |
| SCHEMBL6233429 | 0.89 | ALOX5 (0.54) | ALOX5ESR1LTB4R | |
| SCHEMBL6231507 | 0.86 | ALOX5 (0.57) | ALOX5NPC1HPGDMAPK1HTT | |
| SCHEMBL6233682 | 0.80 | ALOX5 (0.40) | ALOX5MEN1KMT2A | |
| SCHEMBL5587249 | 0.79 | ALOX5 (0.40) | ALOX5NPC1HPGDMAPK1HTT | |
| SCHEMBL6230632 | 0.78 | ESR1 (0.44) | ALOX5NPC1HPGDMAPK1HTT | |
| SCHEMBL6236701 | 0.78 | ALOX5 (0.88) | ALOX5NPC1HPGDMAPK1HTT | |
| SCHEMBL5588832 | 0.76 | HPGD (0.44) | ALOX5NPC1HPGDMAPK1HTT | |
| SCHEMBL6233139 | 0.76 | ALOX5 (0.41) | ALOX5ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |