Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.32 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | QPCT | Q16769 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28901779 | 0.75 | MAPT (0.38) | MAPTCYP19A1KMT2A | |
| SCHEMBL28700417 | 0.70 | MAPT (0.35) | MAPTCYP19A1KMT2A | |
| SCHEMBL22265331 | 0.69 | MAPK1 (0.35) | MAPTCYP19A1 | |
| SCHEMBL24211658 | 0.69 | NFKB1 (0.40) | MAPTCYP19A1CYP24A1NFKB1QPCT | |
| Tetranitromethane SCHEMBL4783630 | 0.68 | ALDH1A1 (0.34) | MAPTCYP19A1CYP24A1 | |
| SCHEMBL14162274 | 0.67 | — | — | |
| SCHEMBL14345997 | 0.67 | — | — | |
| SCHEMBL10649859 | 0.67 | NFKB1 (0.34) | CYP19A1NFKB1QPCTHSD17B10QPCTL | |
| SCHEMBL10649865 | 0.67 | NFKB1 (0.34) | CYP19A1NFKB1QPCTHSD17B10QPCTL | |
| Hydrochloric Acid SCHEMBL27381361 | 0.66 | NFKB1 (0.37) | CYP19A1CYP24A1NFKB1QPCTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534239-A2 | PREPARATION OF SUBMICRON SIZED PARTICLES WITH POLYMORPH CONTROL AND NEW POLYMORPH OF ITRACONAZOLE | BAXTER INTERNATIONAL INC. (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004054500-A2 | PREPARATION OF SUBMICRON SIZED PARTICLES WITH POLYMORPH CONTROL AND NEW POLYMORPH OF ITRACONAZOLE | BAXTER INTERNATIONAL INC. (US) | 2004-07-01 | — | — | WO | disclosed |
| US-20030096013-A1 | Preparation of submicron sized particles with polymorph control | BAXTER INTERNATIONAL INC. | 2003-05-22 | — | — | US | disclosed |