Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 13/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | MPL | P40238 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21116892 | 0.77 | KIF11 (0.76) | KIF11CYP11B2CYP11B1 | |
| SCHEMBL6239140 | 0.76 | KIF11 (0.60) | KIF11PTGS1PTGS2 | |
| SCHEMBL3903111 | 0.74 | KIF11 (0.72) | KIF11CYP11B2CYP11B1 | |
| SCHEMBL3899619 | 0.74 | KIF11 (1.00) | KIF11CYP11B2CYP11B1 | |
| SCHEMBL9428728 | 0.74 | KIF11 (0.52) | KIF11 | |
| SCHEMBL3896158 | 0.74 | KIF11 (0.72) | KIF11CYP11B2CYP11B1 | |
| SCHEMBL3895116 | 0.71 | KIF11 (0.68) | KIF11CYP11B2CYP11B1PTGS1PTGS2 | |
| SCHEMBL22834330 | 0.71 | APP (0.50) | — | |
| SCHEMBL25165736 | 0.71 | KIF11 (0.42) | KIF11CYP11B2CYP11B1 | |
| SCHEMBL24342416 | 0.70 | TSHR (0.50) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | disclosed |