Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 13/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13742955 | 0.84 | RAB9A (0.46) | KIF11NPC1RAB9ACA12CA1 | |
| SCHEMBL3562110 | 0.82 | KIF11 (0.46) | KIF11NPC1RAB9A | |
| SCHEMBL13742917 | 0.81 | CA1 (0.53) | PTGS2PTGS1NPC1RAB9ACA12 | |
| SCHEMBL6234020 | 0.78 | CA1 (0.58) | KIF11PTGS2PTGS1NPC1RAB9A | |
| SCHEMBL6236816 | 0.76 | KIF11 (0.59) | KIF11PTGS2PTGS1 | |
| SCHEMBL18118201 | 0.76 | CA1 (0.56) | PTGS2PTGS1NPC1RAB9ACA12 | |
| SCHEMBL3480234 | 0.73 | SNCA (0.63) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL3567560 | 0.72 | NPC1 (0.43) | NPC1RAB9A | |
| SCHEMBL5528573 | 0.72 | KIF11 (0.74) | KIF11PTGS2PTGS1 | |
| SCHEMBL5531427 | 0.72 | KIF11 (0.74) | KIF11PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | disclosed |