Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.42 |
| ▸ | NAMPT | P43490 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3257474 | 0.91 | OPRD1 (0.52) | OPRD1OPRK1GPR119NAMPTPOLB | |
| SCHEMBL18625253 | 0.80 | OPRD1 (0.44) | OPRD1OPRK1NAMPT | |
| SCHEMBL3258235 | 0.77 | OPRD1 (0.50) | OPRD1OPRK1GPR119NAMPTPOLB | |
| SCHEMBL4979176 | 0.75 | OPRD1 (0.46) | OPRD1OPRK1GPR119NAMPTPOLB | |
| SCHEMBL15941960 | 0.74 | OPRD1 (0.38) | OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL15803585 | 0.74 | NR1H2 (0.42) | OPRD1OPRK1GPR119NAMPT | |
| SCHEMBL5473953 | 0.72 | GPR119 (0.53) | OPRD1OPRK1GPR119POLBUSP2 | |
| SCHEMBL16173468 | 0.72 | OPRD1 (0.50) | OPRD1OPRK1GPR119NAMPTPOLB | |
| SCHEMBL25458288 | 0.71 | GPR119 (0.50) | OPRD1OPRK1GPR119NAMPTPOLB | |
| SCHEMBL16992322 | 0.71 | OPRD1 (0.49) | OPRD1OPRK1GPR119NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | disclosed |