Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28559290 | 0.81 | ATR (0.44) | ALOX5APFEN1GABRG2GABRB3GABRA3 | |
| SCHEMBL14065408 | 0.80 | HTT (0.41) | ALOX5APFEN1ADORA1ADORA2AADORA2B | |
| SCHEMBL6240121 | 0.70 | MPL (0.40) | ALOX5APFEN1ATR | |
| SCHEMBL6239462 | 0.70 | NOTUM (0.44) | ALOX5APFEN1 | |
| SCHEMBL25983090 | 0.70 | AR (0.46) | ARPDK2 | |
| SCHEMBL582563 | 0.69 | CYP1A2 (0.47) | ARPDK2 | |
| SCHEMBL21357776 | 0.68 | AR (0.47) | ARGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL14065409 | 0.68 | CA1 (0.40) | ADORA1ADORA2AADORA2B | |
| SCHEMBL30635279 | 0.67 | AR (0.45) | ARGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL20242216 | 0.66 | MPL (0.51) | ALOX5APFEN1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | disclosed |