Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 14/20 | 0.58 |
| ▸ | RARG | P13631 | 10/20 | 0.58 |
| ▸ | RXRA | P19793 | 9/20 | 0.58 |
| ▸ | RARA | P10276 | 12/20 | 0.52 |
| ▸ | RXRB | P28702 | 6/20 | 0.47 |
| ▸ | RXRG | P48443 | 6/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6241853 | 0.92 | RARB (0.53) | RARBRARGRXRARARARXRB | |
| SCHEMBL6244138 | 0.91 | RXRA (0.60) | RARBRARGRXRARARARXRB | |
| SCHEMBL6243033 | 0.89 | RARB (0.53) | RARBRARGRXRARARARXRB | |
| SCHEMBL6242987 | 0.88 | RARB (0.49) | RARBRARGRXRARARARXRB | |
| SCHEMBL6239480 | 0.88 | RARG (0.49) | RARBRARGRXRARARARXRB | |
| SCHEMBL6239181 | 0.85 | RXRA (0.55) | RARBRARGRXRARARARXRB | |
| SCHEMBL6243493 | 0.84 | RXRA (0.47) | RARBRARGRXRARARARXRB | |
| SCHEMBL6243135 | 0.84 | RXRA (0.53) | RARBRARGRXRARARARXRB | |
| SCHEMBL6242125 | 0.81 | RXRA (0.52) | RARBRARGRXRARARARXRB | |
| SCHEMBL6243517 | 0.80 | RXRA (0.46) | RARBRARGRXRARARARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005017185-A2 | HEPATOCYTE NUCLEAR FACTOR 4α MODULATOR COMPOUNDS | LIGAND PHARMCEUTICALS INCORPORATED (US) | 2005-02-24 | — | — | WO | claimed |
| WO-2005017185-A2 | HEPATOCYTE NUCLEAR FACTOR 4α MODULATOR COMPOUNDS | LIGAND PHARMCEUTICALS INCORPORATED (US) | 2005-02-24 | — | — | WO | disclosed |