Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 9/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1337055 | 0.83 | MAPT (0.55) | DYRK1AMAPTGAAMEN1KMT2A | |
| SCHEMBL14988514 | 0.80 | SCN2A (0.59) | MAPTNPSR1MEN1KMT2AHSP90AA1 | |
| SCHEMBL30794335 | 0.80 | MAPT (0.60) | MAPTNPSR1GAAMEN1KMT2A | |
| SCHEMBL29180298 | 0.80 | MAPT (0.60) | MAPTNPSR1GAAMEN1KMT2A | |
| SCHEMBL2402918 | 0.79 | DHODH (0.48) | XDHDYRK1AKCNH2SCN10AMAPT | |
| SCHEMBL6231939 | 0.79 | RAB9A (0.60) | MAPTCASP3SENP7NPC1RAB9A | |
| SCHEMBL1723569 | 0.78 | MAPT (0.57) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL3409448 | 0.78 | DYRK1A (0.50) | XDHDYRK1AKCNH2SCN10AFYN | |
| SCHEMBL8350438 | 0.77 | DYRK1A (0.52) | XDHDYRK1AKCNH2SCN10AFYN | |
| SCHEMBL14988369 | 0.76 | NPC1 (0.50) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | disclosed |