Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 11/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3409448 | 0.84 | DYRK1A (0.50) | DYRK1AKCNH2SCN10AXDHFYN | |
| SCHEMBL12019038 | 0.81 | KDM1A (0.58) | DYRK1ACYP3A4CYP2A6FYN | |
| SCHEMBL13471699 | 0.81 | CCR1 (0.48) | KCNH2SCN10ACYP3A4CYP2A6 | |
| SCHEMBL8303713 | 0.79 | PIM1 (0.51) | DYRK1AKCNH2SCN10AXDHFYN | |
| SCHEMBL31356744 | 0.79 | ALDH1A1 (0.48) | DYRK1AKCNH2SCN10AXDHFYN | |
| SCHEMBL503090 | 0.79 | CYP3A4 (0.63) | CYP3A4CYP2A6 | |
| SCHEMBL8309977 | 0.78 | LDHA (0.57) | DYRK1AXDHFYNDHODH | |
| SCHEMBL1044062 | 0.78 | CYP1A2 (0.51) | DYRK1AKCNH2SCN10AXDHDHODH | |
| SCHEMBL17100103 | 0.77 | GRM5 (0.67) | DYRK1AKCNH2SCN10AXDHCTSS | |
| SCHEMBL10093051 | 0.77 | DHODH (0.57) | PDE10ACYP3A4CYP2A6DHODHCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051252-A2 | NOVEL AMIDE COMPOUND, METHOD FOR PRODUCING THE SAME, AND MITICIDE | INSECTICIDES (INDIA) LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |
| US-5872136-A | Arylheteroaryl inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1999-02-16 | — | — | US | disclosed |
| EP-0891361-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036901-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |