SCHEMBL62370

SCHEMBL62370

CCN(CC)c1ccc2nc3c4cc(OCCN)ccc4c(=O)cc-3oc2c1

nearest known ligand 0.77

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SCP2 P22307 1/20 0.77
MEN1 O00255 1/20 0.67
NPC1 O15118 1/20 0.67
POLB P06746 1/20 0.67
RAB9A P51151 1/20 0.67
KMT2A Q03164 1/20 0.67
GPR84 Q9NQS5 10/20 0.53
APP P05067 1/20 0.41
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41
SIGMAR1 Q99720 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19646592 0.90 SCP2 (0.77) SCP2MEN1NPC1POLBRAB9A
SCHEMBL16812947 0.89 SCP2 (0.74) SCP2MEN1NPC1POLBRAB9A
SCHEMBL14267417 0.87 SCP2 (1.00) SCP2MEN1NPC1POLBRAB9A
SCHEMBL26434988 0.87 SCP2 (0.75) SCP2MEN1NPC1POLBRAB9A
SCHEMBL25188913 0.86 SCP2 (0.71) SCP2MEN1NPC1POLBRAB9A
SCHEMBL26434823 0.86 SCP2 (0.76) SCP2MEN1NPC1POLBRAB9A
SCHEMBL3501312 0.86 SCP2 (0.82) SCP2MEN1NPC1POLBRAB9A
SCHEMBL13201656 0.86 SCP2 (0.76) SCP2MEN1NPC1POLBRAB9A
SCHEMBL7812704 0.86 SCP2 (0.93) SCP2MEN1NPC1POLBRAB9A
SCHEMBL5917041 0.86 SCP2 (0.65) SCP2MEN1NPC1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107249589-B Physiologically active substance-binding block copolymer 日本化药株式会社 2021-06-08 CN disclosed
US-20180334540-A1 Polymeric Derivative Of Macrolide Immunosuppressant NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2018-11-22 US disclosed
EP-3378494-A1 POLYMERIC DERIVATIVE OF MACROLIDE IMMUNOSUPPRESSANT Nippon Kayaku Kabushiki Kaisha (JP) 2018-09-26 EP disclosed
US-8129525-B2 Long wavelength thiol-reactive fluorophores BECTON DICKINSON AND COMPANY (US) 2012-03-06 US disclosed
US-8129525-B2 Long wavelength thiol-reactive fluorophores BECTON DICKINSON AND COMPANY (US) 2012-03-06 US disclosed
US-8071794-B2 Long wavelength thiol-reactive fluorophores BECTON, DICKINSON AND COMPANY (US) 2011-12-06 US disclosed
US-8071794-B2 Long wavelength thiol-reactive fluorophores BECTON, DICKINSON AND COMPANY (US) 2011-12-06 US disclosed
US-20110184168-A1 LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES BECTON, DICKINSON AND COMPANY (US) 2011-07-28 US disclosed
US-20110184168-A1 LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES BECTON, DICKINSON AND COMPANY (US) 2011-07-28 US disclosed
US-7767821-B2 Long wavelength thiol-reactive fluorophores BECTON, DICKINSON & COMPANY (US) 2010-08-03 US disclosed
US-7767821-B2 Long wavelength thiol-reactive fluorophores BECTON, DICKINSON & COMPANY (US) 2010-08-03 US disclosed
US-20100167417-A1 LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES BECTON, DICKINSON AND COMPANY (US) 2010-07-01 US disclosed
US-20100167417-A1 LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES BECTON, DICKINSON AND COMPANY (US) 2010-07-01 US disclosed
US-20100003763-A1 LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES BECTON, DICKINSON AND COMPANY (US) 2010-01-07 US disclosed
US-20100003763-A1 LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES BECTON, DICKINSON AND COMPANY (US) 2010-01-07 US disclosed
US-7563891-B2 Long wavelength thiol-reactive fluorophores BECTON, DICKINSON & COMPANY (US) 2009-07-21 US disclosed
US-7563891-B2 Long wavelength thiol-reactive fluorophores BECTON, DICKINSON & COMPANY (US) 2009-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100167417-A1 LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES NUCB2, NDC1, NCBP1 SCP2 2959/4885MEN1 4815/4885NPC1 2664/4885
US-20100003763-A1 LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES NUCB2, NDC1, NCBP1 SCP2 2959/4885MEN1 4815/4885NPC1 2664/4885
US-20110184168-A1 LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES NUCB2, NDC1, NCBP1 SCP2 2959/4885MEN1 4815/4885NPC1 2664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.