SCHEMBL16812947

SCHEMBL16812947

CCN(CC)c1ccc2nc3c4cc(OCBr)ccc4c(=O)cc-3oc2c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCP2 P22307 1/20 0.74
MEN1 O00255 2/20 0.69
KMT2A Q03164 2/20 0.69
NPC1 O15118 1/20 0.69
POLB P06746 1/20 0.69
RAB9A P51151 1/20 0.69
GPR84 Q9NQS5 10/20 0.51
ALDH1A1 P00352 2/20 0.41
GLA P06280 2/20 0.41
CYP3A4 P08684 2/20 0.41
CASP1 P29466 2/20 0.41
CASP7 P55210 2/20 0.41
ATM Q13315 2/20 0.41
HSD17B10 Q99714 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
IGLV6-57 P01721 1/20 0.41
HPGD P15428 1/20 0.41
MAPK1 P28482 1/20 0.41
HIF1A Q16665 1/20 0.41
BCHE P06276 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19646592 0.92 SCP2 (0.77) SCP2MEN1KMT2ANPC1POLB
SCHEMBL62370 0.89 SCP2 (0.77) SCP2MEN1KMT2ANPC1POLB
SCHEMBL25188913 0.88 SCP2 (0.71) SCP2MEN1KMT2ANPC1POLB
SCHEMBL26434823 0.88 SCP2 (0.76) SCP2MEN1KMT2ANPC1POLB
SCHEMBL3501312 0.88 SCP2 (0.82) SCP2MEN1KMT2ANPC1POLB
SCHEMBL26434988 0.87 SCP2 (0.75) SCP2MEN1KMT2ANPC1POLB
SCHEMBL17230446 0.87 MEN1 (0.67) SCP2MEN1KMT2ANPC1POLB
SCHEMBL14267417 0.85 SCP2 (1.00) SCP2MEN1KMT2ANPC1POLB
SCHEMBL13201656 0.84 SCP2 (0.76) SCP2MEN1KMT2ANPC1POLB
SCHEMBL7812704 0.84 SCP2 (0.93) SCP2MEN1KMT2ANPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2890981-B1 SENESCENCE TRACERS UNIV TUEBINGEN MEDIZINISCHE FAKULTAET (DE) 2018-11-07 EP disclosed
US-9829481-B2 Senescence tracers EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) 2017-11-28 US disclosed
US-20150168374-A1 SENESCENCE TRACERS EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) 2015-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150168374-A1 SENESCENCE TRACERS AGER, FUCA1, FUCA2 SCP2 4212/4885MEN1 1187/4885KMT2A 1804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.