Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 14/20 | 0.51 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | PTPRC | P08575 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908559 | 0.93 | ALDH1A1 (0.53) | POLBALDH1A1RXFP1IDO1TDO2 | |
| Ethylene SCHEMBL8908925 | 0.89 | ALDH1A1 (0.50) | POLBALDH1A1RXFP1IDO1TDO2 | |
| SCHEMBL9815972 | 0.81 | PTPRC (0.42) | POLBALDH1A1RXFP1IDO1TDO2 | |
| SCHEMBL8908233 | 0.75 | KMT2A (0.41) | POLBALDH1A1RXFP1IDO1TDO2 | |
| SCHEMBL8908230 | 0.75 | KMT2A (0.41) | POLBALDH1A1RXFP1IDO1TDO2 | |
| SCHEMBL7816679 | 0.74 | IDO1 (0.55) | POLBALDH1A1RXFP1IDO1TDO2 | |
| SCHEMBL30204979 | 0.73 | ALDH1A1 (1.00) | POLBALDH1A1RXFP1IDO1TDO2 | |
| SCHEMBL414535 | 0.73 | ALDH1A1 (1.00) | POLBALDH1A1RXFP1IDO1TDO2 | |
| SCHEMBL1888851 | 0.72 | KDM4E (0.52) | POLBALDH1A1RAB9A | |
| Anthraquinone SCHEMBL28787967 | 0.69 | ALDH1A1 (0.50) | POLBALDH1A1IDO1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016000-A1 | DERIVATIVES OF CYCLIC QUINONE AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2005-02-24 | — | — | WO | disclosed |