SCHEMBL623711

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL623298	0.89	PKM (0.43)	PKMCFTRACACBNAMPTHRH4
	SCHEMBL623300	0.89	ITGB2 (0.37)	ACACBITGB2ICAM1ITGALSCN9A
	SCHEMBL624384	0.85	MEN1 (0.34)	ACACBALDH1A1LMNAHPGDSMN1; SMN2
	SCHEMBL623188	0.83	KCNT1 (0.40)	ACACBITGB2ICAM1ITGALHRH4
	SCHEMBL623770	0.83	PSMB8 (0.38)	ACACBALDH1A1HPGDMEN1KMT2A
	SCHEMBL624375	0.82	HRH3 (0.37)	ACACBITGB2ICAM1ITGALSCN9A
	SCHEMBL624199	0.81	CYP1A2 (0.48)	CFTRHRH4KDM4EALDH1A1HPGD
	SCHEMBL624371	0.80	KCNK3 (0.44)	ACACBITGB2ICAM1ITGALSCN9A
	SCHEMBL623262	0.78	ACACB (0.40)	ACACBITGB2ICAM1ITGALSCN9A
	SCHEMBL624504	0.78	CYP2C19 (0.45)	CFTRSCN9AHPGDCYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.