SCHEMBL6237145

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18329658	0.92	SMN1; SMN2 (0.44)	ALDH1A1KDM4EGAAKMT2AMAPK8
	SCHEMBL30071045	0.87	ALDH1A1 (0.50)	ALDH1A1KDM4EGAAKMT2APHF8
	SCHEMBL316348	0.86	SMN1; SMN2 (0.48)	ALDH1A1KDM4EGAAKMT2AMAPK8
	SCHEMBL7914274	0.85	GAA (0.43)	ALDH1A1KDM4EGAAKMT2AMAPK8
	SCHEMBL4889822	0.85	GAA (0.46)	ALDH1A1KDM4EGAAKMT2AMAPK8
	SCHEMBL12352252	0.84	GAA (0.50)	ALDH1A1KDM4EGAAKMT2AMAPK8
	SCHEMBL24850469	0.83	GAA (0.45)	ALDH1A1KDM4EGAAKMT2AMAPK8
	SCHEMBL23783503	0.83	GAA (0.44)	ALDH1A1KDM4EGAAKMT2AMAPK8
	SCHEMBL22585065	0.83	ALDH1A1 (0.46)	ALDH1A1KDM4EGAAKMT2APHF8
	SCHEMBL12846025	0.82	GAA (0.43)	ALDH1A1KDM4EGAAKMT2AMAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.