Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237247 | 1.00 | THRB (0.40) | THRB | |
| SCHEMBL6245430 | 0.92 | THRB (0.31) | THRB | |
| SCHEMBL6245427 | 0.92 | THRB (0.31) | THRB | |
| SCHEMBL6240610 | 0.83 | THRB (0.40) | THRB | |
| SCHEMBL6239871 | 0.79 | — | — | |
| SCHEMBL6239868 | 0.79 | — | — | |
| SCHEMBL6242492 | 0.78 | THRB (0.40) | THRB | |
| SCHEMBL6242497 | 0.78 | THRB (0.40) | THRB | |
| SCHEMBL1617979 | 0.76 | THRB (0.35) | THRB | |
| SCHEMBL3675043 | 0.76 | THRB (0.35) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043297-B1 | PROCESS FOR THE PREPARATION OF COMPOUNDS HAVING -CH2-CHF- GROUPS | NIPPON ZEON CO (JP) | 2005-06-29 | — | — | EP | disclosed |
| US-6395700-B1 | CATALYTIC HYDROGENATION | NIPPON ZEON CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |
| EP-1043297-A1 | PROCESS FOR THE PREPARATION OF COMPOUNDS HAVING -CH2-CHF- GROUPS | Nippon Zeon Co., Ltd. (JP) | 2000-10-11 | — | — | EP | disclosed |