⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239868 | 1.00 | — | — | |
| SCHEMBL7984584 | 0.82 | — | — | |
| SCHEMBL6245427 | 0.81 | THRB (0.31) | — | |
| SCHEMBL6245430 | 0.81 | THRB (0.31) | — | |
| SCHEMBL6244381 | 0.80 | — | — | |
| SCHEMBL6237247 | 0.79 | THRB (0.40) | — | |
| SCHEMBL6237245 | 0.79 | THRB (0.40) | — | |
| SCHEMBL6378715 | 0.78 | — | — | |
| SCHEMBL22121299 | 0.75 | — | — | |
| SCHEMBL1219873 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043297-B1 | PROCESS FOR THE PREPARATION OF COMPOUNDS HAVING -CH2-CHF- GROUPS | NIPPON ZEON CO (JP) | 2005-06-29 | — | — | EP | disclosed |
| CN-1127462-C | Process for preparation of compounds having-CH2-CHF-groups | NIPPON ZEON CO (JP) | 2003-11-12 | — | — | CN | disclosed |
| US-6395700-B1 | CATALYTIC HYDROGENATION | NIPPON ZEON CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |
| EP-0913380-B1 | PROCESS FOR THE PREPARATION OF FLUORINATED OLEFIN | AGENCY IND SCIENCE TECHN (JP) | 2002-04-03 | — | — | EP | disclosed |
| US-6211420-B1 | REACTING HALOGENATED OLEFIN WITH ALKALI METAL FLUORIDE IN PRESENCE OF SPECIFIED ORGANIC HALOGEN-CONTAINING COMPOUND TO PRODUCE FLUORINATED OLEFIN | JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2001-04-03 | — | — | US | disclosed |
| CN-1286672-A | Process for preparation of compounds having-CH2-CHF-groups | NIPPON ZEON CO (JP) | 2001-03-07 | — | — | CN | disclosed |
| EP-1043297-A1 | PROCESS FOR THE PREPARATION OF COMPOUNDS HAVING -CH2-CHF- GROUPS | Nippon Zeon Co., Ltd. (JP) | 2000-10-11 | — | — | EP | disclosed |
| EP-0913380-A1 | PROCESS FOR THE PREPARATION OF FLUORINATED OLEFIN | Japan as represented by Director-General, Agency of Industrial Science and Technology (JP) | 1999-05-06 | — | — | EP | disclosed |